Parametric and non-parametric gradient matching for network inference: a comparison

Abstract Background Reverse engineering of gene regulatory networks from time series gene-expression data is a challenging problem, not only because of the vast sets of candidate interactions but also due to the stochastic nature of gene expression. We limit our analysis to nonlinear differential eq...

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Bibliographic Details
Main Authors: Leander Dony, Fei He, Michael P. H. Stumpf
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2590-7