Modulation of FoxO1 Expression by miR-21 to Promote Growth of Pancreatic Ductal Adenocarcinoma

Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal primary tumors in humans, with undetermined tumorigenesis. Although previous work by us, and by others, has clearly demonstrated an involvement of miR-21 in the growth of PDAC, the underlying mechanism has not been clarifi...

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Bibliographic Details
Main Authors: Weifeng Song, Qi Li, Lei Wang, Liwei Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/369686