Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of PPARdelta.

BACKGROUND:Members of the Peroxisome Proliferator Activated Receptor, PPAR, subfamily of nuclear receptors display complex opposing and overlapping functions and a wide range of pharmacological and molecular genetic tools have been used to dissect their specific functions. Non-agonist bound PPARdelt...

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Bibliographic Details
Main Authors: Mattias C U Gustafsson, Deborah Knight, Colin N A Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737640?pdf=render