CB1 Receptor-Dependent and Independent Induction of Lipolysis in Primary Rat Adipocytes by the Inverse Agonist Rimonabant (SR141716A)

CB1 Receptor-Dependent and Independent Induction of Lipolysis in Primary Rat Adipocytes by the Inverse Agonist Rimonabant (SR141716A)

(1) Background: Acute administration of the cannabinoid receptor 1 (CB1R) inverse agonist Rimonabant (SR141716A) to fed Wistar rats was shown to elicit a rapid and short-lasting elevation of serum free fatty acids. (2) Methods: The effect of Rimonabant on lipolysis in isolated primary rat adipocytes...

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Bibliographic Details
Main Authors: Günter A. Müller, Andreas W. Herling, Susanne Wied, Timo D. Müller
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
cyclic adenosine monophosphate (camp)-dependent signaling
cannabinoid receptor 1 (cb1r)
hormone-sensitive lipase (hsl)
interfacial activation
lipid droplets (ld)
lipolysis
obesity
rimonabant
Online Access:https://www.mdpi.com/1420-3049/25/4/896

Internet

https://www.mdpi.com/1420-3049/25/4/896

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