Brain Activation by H1 Antihistamines Challenges Conventional View of Their Mechanism of Action in Motion Sickness: A Behavioral, c-Fos and Physiological Study in Suncus murinus (House Musk Shrew)

Brain Activation by H1 Antihistamines Challenges Conventional View of Their Mechanism of Action in Motion Sickness: A Behavioral, c-Fos and Physiological Study in Suncus murinus (House Musk Shrew)

Motion sickness occurs under a variety of circumstances and is common in the general population. It is usually associated with changes in gastric motility, and hypothermia, which are argued to be surrogate markers for nausea; there are also reports that respiratory function is affected. As laborator...

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Bibliographic Details
Main Authors: Longlong Tu, Zengbing Lu, Karolina Dieser, Christina Schmitt, Sze Wa Chan, Man P. Ngan, Paul L. R. Andrews, Eugene Nalivaiko, John A. Rudd
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Physiology
Subjects:
gastric myoelectric activity
histamine H1 receptors
hypothermia
motion sickness
muscarinic receptors
respiration pattern
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00412/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00412/full

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