Molecular interpretation of ACTH-β-endorphin coaggregation: relevance to secretory granule biogenesis.

Molecular interpretation of ACTH-β-endorphin coaggregation: relevance to secretory granule biogenesis.

Peptide/protein hormones could be stored as non-toxic amyloid-like structures in pituitary secretory granules. ACTH and β-endorphin are two of the important peptide hormones that get co-stored in the pituitary secretory granules. Here, we study molecular interactions between ACTH and β-endorphin and...

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Bibliographic Details
Main Authors: Srivastav Ranganathan, Pradeep K Singh, Uday Singh, Praful S Singru, Ranjith Padinhateeri, Samir K Maji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293876?pdf=render

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http://europepmc.org/articles/PMC3293876?pdf=render

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