Regulation of ClC-2 Activity by SPAK and OSR1

Background/Aims: SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) are powerful regulators of diverse transport processes. Both kinases are activated by cell shrinkage and participate in stimulation of regulatory cell volume increase (RVI). Execution of...

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Bibliographic Details
Main Authors: Jamshed Warsi, Zohreh Hosseinzadeh, Bernat Elvira, Rosi Bissinger, Ekaterina Shumilina, Florian Lang
Format: Article
Language:English
Published: Karger Publishers 2014-10-01
Series:Kidney & Blood Pressure Research
Subjects:
WNK
Online Access:http://www.karger.com/Article/FullText/355816