Prognosis prediction model for conversion from mild cognitive impairment to Alzheimer’s disease created by integrative analysis of multi-omics data

Prognosis prediction model for conversion from mild cognitive impairment to Alzheimer’s disease created by integrative analysis of multi-omics data

Abstract Background Mild cognitive impairment (MCI) is a precursor to Alzheimer’s disease (AD), but not all MCI patients develop AD. Biomarkers for early detection of individuals at high risk for MCI-to-AD conversion are urgently required. Methods We used blood-based microRNA expression profiles and...

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Bibliographic Details
Main Authors: Daichi Shigemizu, Shintaro Akiyama, Sayuri Higaki, Taiki Sugimoto, Takashi Sakurai, Keith A. Boroevich, Alok Sharma, Tatsuhiko Tsunoda, Takahiro Ochiya, Shumpei Niida, Kouichi Ozaki
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Biomarkers for early diagnosis
eQTL effect
Online Access:http://link.springer.com/article/10.1186/s13195-020-00716-0

Internet

http://link.springer.com/article/10.1186/s13195-020-00716-0

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