PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1.

PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1.

The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress. The analysis of 8-oxodeoxyguanosine (8-oxodGuo) level in leukocyte DNA of healthy controls (138 individuals), patients with benign adenomas (AD, 137 individuals) and with malignant carcinomas (CRC, 169 indivi...

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Bibliographic Details
Main Authors: Tomasz Dziaman, Hubert Ludwiczak, Jaroslaw M Ciesla, Zbigniew Banaszkiewicz, Alicja Winczura, Mateusz Chmielarczyk, Ewa Wisniewska, Andrzej Marszalek, Barbara Tudek, Ryszard Olinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4272268?pdf=render

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http://europepmc.org/articles/PMC4272268?pdf=render

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