The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense

The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense

The transcriptional coactivator Yes-associated protein (YAP) plays an important role in organ-size control and tumorigenesis. However, how Yap gene expression is regulated remains unknown. This study shows that the Ets family member GABP binds to the Yap promoter and activates YAP transcription. Th...

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Bibliographic Details
Main Authors: Hongtan Wu, Yubo Xiao, Shihao Zhang, Suyuan Ji, Luyao Wei, Fuqin Fan, Jing Geng, Jing Tian, Xiufeng Sun, Funiu Qin, Changnan Jin, Jianjun Lin, Zhen-Yu Yin, Ting Zhang, Lianzhong Luo, Yang Li, Siyang Song, Sheng-Cai Lin, Xianming Deng, Fernando Camargo, Joseph Avruch, Lanfen Chen, Dawang Zhou
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713002027

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http://www.sciencedirect.com/science/article/pii/S2211124713002027

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