A Valine Mismatch at Position 129 of MICA Is an Independent Predictor of Cytomegalovirus Infection and Acute Kidney Rejection in Simultaneous Pancreas–Kidney Transplantation Recipients

A Valine Mismatch at Position 129 of MICA Is an Independent Predictor of Cytomegalovirus Infection and Acute Kidney Rejection in Simultaneous Pancreas–Kidney Transplantation Recipients

The polymorphic major histocompatibility complex class I chain-related molecule A (MICA) and its soluble form (sMICA) interact with activating receptor natural-killer group 2 member D (NKG2D) on natural-killer (NK) and T cells, thereby modifying immune responses to transplantation and infectious age...

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Bibliographic Details
Main Authors: Rafael Tomoya Michita, José Artur Bogo Chies, Sabine Schramm, Peter A. Horn, Falko M. Heinemann, Andreas Wunsch, Richard Viebahn, Peter Schenker, Vera Rebmann
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
simultaneous pancreas–kidney transplantation
Val129Met
MICA
cytomegalovirus
acute and latent cytomegalovirus infection
sMICA
dimorphism
genetic predisposition
Online Access:http://www.mdpi.com/1422-0067/19/9/2618

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http://www.mdpi.com/1422-0067/19/9/2618

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