Preserved antigen-specific immune response in patients with multiple sclerosis responding to IFNβ-therapy.

Preserved antigen-specific immune response in patients with multiple sclerosis responding to IFNβ-therapy.

BACKGROUND: Interferon-beta (IFNβ) regulates the expression of a complex set of pro- as well as anti-inflammatory genes. In cohorts of MS patients unstratified for therapeutic response to IFNβ, normal vaccine-specific immune responses have been observed. Data capturing antigen-specific immune respon...

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Bibliographic Details
Main Authors: Matthias Mehling, Stefanie Fritz, Patricia Hafner, Dominik Eichin, Tomomi Yonekawa, Thomas Klimkait, Raija L P Lindberg, Ludwig Kappos, Christoph Hess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818403?pdf=render

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http://europepmc.org/articles/PMC3818403?pdf=render

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