Reversible Neonatal Cholestasis Following In Utero Exposure to Valproic Acid
Valproic acid (VPA) is a branched-chain carboxylic acid with broad anticonvulsant activity. Its spectrum of activity is thought to be mediated by combined molecular effects on intercellular Na+ currents, neuron K+ channels, and inhibition of gamma-aminobutyric acid (GABA) transaminase (1,2). VPA is...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
McGill University
2020-12-01
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| Series: | McGill Journal of Medicine |
| Subjects: | |
| Online Access: | https://mjm.mcgill.ca/article/view/563 |