Histamine H4 receptor regulates IL-6 and INF-γ secretion in native monocytes from healthy subjects and patients with allergic rhinitis

Histamine H4 receptor regulates IL-6 and INF-γ secretion in native monocytes from healthy subjects and patients with allergic rhinitis

Abstract Histamine H1 receptor (H1R) and histamine H4 receptor (H4R) are essential in allergic inflammation. The roles of H4R have been characterized in T cell subsets, whereas the functional properties of H4R in monocytes remain unclear. In the current study, the responses of H4R in peripheral mono...

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Bibliographic Details
Main Authors: Hua Peng, Jian Wang, Xiao Yan Ye, Jie Cheng, Cheng Zhi Huang, Li Yue Li, Tian Ying Li, Chun Wei Li
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Clinical and Translational Allergy
Subjects:
Histamine H4 receptor
Histamine H1 receptor
Allergic rhinitis
Native human monocyte
Th1 and Th2 cytokines
Online Access:http://link.springer.com/article/10.1186/s13601-019-0288-1

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http://link.springer.com/article/10.1186/s13601-019-0288-1

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