Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis (EAE)

Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis (EAE)

Experimental autoimmune encephalomyelitis (EAE) is a murine autoimmune disease used to study multiple sclerosis. We have investigated the immunomodulatory effects of copaiba oil (100, 50 and 25 µg/mL) on NO, H2O2, TNF-α, IFN-γ and IL-17 production in cultured cells from EAE-mice. Copaiba oil (100 µg...

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Bibliographic Details
Main Authors: Débora S. Dias, Lívia B. A. Fontes, Antônio E. M. Crotti, Beatriz J. V. Aarestrup, Fernando M. Aarestrup, Ademar A. da Silva Filho, José O. A. Corrêa
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
multiple sclerosis
experimental autoimmune encephalomyelitis
natural products
immunomodulatory
copaiba oil
Online Access:http://www.mdpi.com/1420-3049/19/8/12814

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http://www.mdpi.com/1420-3049/19/8/12814

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