Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.

The tremendous success of S. aureus as a human pathogen has been explained primarily by its array of virulence factors that enable the organism to evade host immunity. Perhaps equally important, but less well understood, is the importance of the intensity of the host response in determining the exte...

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Bibliographic Details
Main Authors: Dane Parker, Paul J Planet, Grace Soong, Apurva Narechania, Alice Prince
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3930619?pdf=render