Cellular Contact Guidance Emerges from Gap Avoidance

Summary: In the presence of anisotropic biochemical or topographical patterns, cells tend to align in the direction of these cues—a widely reported phenomenon known as “contact guidance.” To investigate the origins of contact guidance, here, we created substrates micropatterned with parallel lines o...

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Bibliographic Details
Main Authors: Antonetta B.C. Buskermolen, Tommaso Ristori, Dylan Mostert, Mark C. van Turnhout, Siamak S. Shishvan, Sandra Loerakker, Nicholas A. Kurniawan, Vikram S. Deshpande, Carlijn V.C. Bouten
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports Physical Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666386420300497