Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation
Abstract We evaluated the role of NLR family pyrin domain containing 3 (NLRP3) inflammasome in sterile corneal inflammation caused by lipopolysaccharide (LPS) or alkali burns in C57BL6 mice or NLRP3 KO (Nlrp3 −/− ) mice. Various molecules related to the NLRP3 inflammasome were upregulated in C57BL6...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-019-46116-9 |