Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells.

Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells.

Hepatocellular carcinoma (HCC) is a global health burden that is associated with limited treatment options and poor patient prognoses. Silybin (SIL), an antioxidant derived from the milk thistle plant (Silybum marianum), has been reported to exert hepatoprotective and antitumorigenic effects both in...

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Bibliographic Details
Main Authors: Song Zhang, Yang Yang, Zhenxing Liang, Weixun Duan, Jian Yang, Juanjuan Yan, Ning Wang, Wenqiang Feng, Meiling Ding, Yongzhan Nie, Zhenxiao Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873967?pdf=render

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http://europepmc.org/articles/PMC3873967?pdf=render

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