Antigen Sampling CSF1R-Expressing Epithelial Cells Are the Functional Equivalents of Mammalian M Cells in the Avian Follicle-Associated Epithelium

Antigen Sampling CSF1R-Expressing Epithelial Cells Are the Functional Equivalents of Mammalian M Cells in the Avian Follicle-Associated Epithelium

The follicle-associated epithelium (FAE) is a specialized structure that samples luminal antigens and transports them into mucosa-associated lymphoid tissues (MALT). In mammals, transcytosis of antigens across the gut epithelium is performed by a subset of FAE cells known as M cells. Here we show th...

Full description

Bibliographic Details
Main Authors: Adam Balic, Cosmin Chintoan-Uta, Prerna Vohra, Kate M. Sutton, Robin L. Cassady-Cain, Tuan Hu, David S. Donaldson, Mark P. Stevens, Neil A. Mabbott, David A. Hume, Helen M. Sang, Lonneke Vervelde
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
mucosa-associated lymphoid tissue
antigen uptake
M cell
CSF1R
avian
Salmonella
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02495/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02495/full

Similar Items