Comparative Untargeted Metabolomic Profiling of Induced Mitochondrial Fusion in Pancreatic Cancer

Comparative Untargeted Metabolomic Profiling of Induced Mitochondrial Fusion in Pancreatic Cancer

Mitochondria are dynamic organelles that constantly alter their shape through the recruitment of specialized proteins, like mitofusin-2 (Mfn2) and dynamin-related protein 1 (Drp1). Mfn2 induces the fusion of nearby mitochondria, while Drp1 mediates mitochondrial fission. We previously found that the...

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Bibliographic Details
Main Authors: Nicholas D. Nguyen, Meifang Yu, Vinit Y. Reddy, Ariana C. Acevedo-Diaz, Enzo C. Mesarick, Joseph Abi Jaoude, Min Yuan, John M. Asara, Cullen M. Taniguchi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
mitochondrial morphology
fusion
fission
mitofusin-2
leflunomide
pancreatic cancer
Online Access:https://www.mdpi.com/2218-1989/11/9/627

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https://www.mdpi.com/2218-1989/11/9/627

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