Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions

Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions

Endothelin (ET)-1 is involved in various fibrotic diseases. However, its implication in pleural fibrosis remains unknown. We aimed to study the profibrotic role of ET-1 in tuberculous pleural effusion (TBPE). The pleural effusion ET-1 levels were measured among 68 patients including transudative ple...

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Bibliographic Details
Main Authors: Zhung-Han Wu, Jie-Heng Tsai, Cheng-Ying Hsieh, Wei-Lin Chen, Chi-Li Chung
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Journal of Clinical Medicine
Subjects:
endothelin-1
extracellular matrix
mesothelial mesenchymal transition
pleural fibrosis
pleural mesothelial cell
residual pleura thickening
tuberculous pleural effusion
Online Access:https://www.mdpi.com/2077-0383/8/4/426

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https://www.mdpi.com/2077-0383/8/4/426

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