Biomimetic oxidation of carbamazepine with hydrogen peroxide catalyzed by a manganese porphyrin

This laboratory project is planned for an undergraduate chemistry laboratory in which students prepare a manganese porphyrin able to mimic the oxidative metabolism of carbamazepine, one of the most frequently prescribed drugs in the treatment of epilepsy. The in vitro oxidation of carbamazepine resu...

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Bibliographic Details
Main Authors: Cláudia M. B. Neves, Mário M. Q. Simões, Fernando M. J. Domingues, M. Graça P. M. S. Neves, José A. S. Cavaleiro
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000700033&lng=en&tlng=en