A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii

A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii

Searching for new antimicrobials is a pressing issue to conquer the emergence of multidrug-resistant (MDR) bacteria and fungi. Antimicrobial peptides (AMPs) usually have antimicrobial mechanisms different from those of traditional antibiotics and bring new hope in the discovery of new antimicrobials...

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Bibliographic Details
Main Authors: Sung-Pang Chen, Eric H-L Chen, Sheng-Yung Yang, Pin-Shin Kuo, Hau-Ming Jan, Tsai-Chen Yang, Ming-Yen Hsieh, Kung-Ta Lee, Chun-Hung Lin, Rita P-Y Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptide
antibiotic-resistant
Acinetobacter baumannii
lipid
membrane
drug-resistant
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.678330/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.678330/full

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