PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

Extensive evidence from epidemiologic, genetic, and clinical intervention studies has indisputably shown that elevated low-density lipoprotein cholesterol (LDL-C) concentrations play a central role in the pathophysiology of atherosclerotic cardiovascular disease. Apart from LDL-C, also triglycerides...

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Bibliographic Details
Main Authors: Ioanna Andreadou, Maria Tsoumani, Gemma Vilahur, Ignatios Ikonomidis, Lina Badimon, Zoltán V. Varga, Péter Ferdinandy, Rainer Schulz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
dyslipidemia
heart failure
ischaemia
LDL cholesterol
myocardial infarction
PCSK9
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.602497/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.602497/full

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