Noninvasive monitoring of placenta-specific transgene expression by bioluminescence imaging.

BACKGROUND: Placental dysfunction underlies numerous complications of pregnancy. A major obstacle to understanding the roles of potential mediators of placental pathology has been the absence of suitable methods for tissue-specific gene manipulation and sensitive assays for studying gene functions i...

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Bibliographic Details
Main Authors: Xiujun Fan, Peigen Ren, Sabita Dhal, Gill Bejerano, Stuart B Goodman, Maurice L Druzin, Sanjiv S Gambhir, Nihar R Nayak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025029?pdf=render