Noise-Induced Cochlear Damage Involves PPAR Down-Regulation through the Interplay between Oxidative Stress and Inflammation

Noise-Induced Cochlear Damage Involves PPAR Down-Regulation through the Interplay between Oxidative Stress and Inflammation

The cross-talk between oxidative stress and inflammation seems to play a key role in noise-induced hearing loss. Several studies have addressed the role of PPAR receptors in mediating antioxidant and anti-inflammatory effects and, although its protective activity has been demonstrated in several tis...

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Bibliographic Details
Main Authors: Fabiola Paciello, Anna Pisani, Rolando Rolesi, Vincent Escarrat, Jacopo Galli, Gaetano Paludetti, Claudio Grassi, Diana Troiani, Anna Rita Fetoni
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antioxidants
Subjects:
acoustic trauma
cochlea
NF-κB
ROS
IL-1β
Q-ter
Online Access:https://www.mdpi.com/2076-3921/10/8/1188

Internet

https://www.mdpi.com/2076-3921/10/8/1188

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