Neogenin as a receptor for early cell fate determination in preimplantation mouse embryos.

The first cell lineage determination in embryos takes place when two cell populations are set apart, each differentiating into the trophectoderm (TE) and inner cell mass (ICM), respectively. It is widely believed that position/polarity cues play a key role in triggering this differentiation, but it...

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Bibliographic Details
Main Authors: Jae Ho Lee, Sung Sook Choi, Hae-Won Kim, Wen Cheng Xiong, Churl K Min, Sang Jin Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094428?pdf=render