Anti-Inflammatory Polymeric Nanoparticles Based on Ketoprofen and Dexamethasone

Anti-Inflammatory Polymeric Nanoparticles Based on Ketoprofen and Dexamethasone

Polymeric nanoparticles that combine dexamethasone and naproxen reduce inflammation and synergistically inhibit Interleukin-12b (<i>Il12b</i>) transcription in macrophages. This effect can be the result of a cyclooxygenase-dependent or a cyclooxygenase-independent mechanism. The aim of t...

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Bibliographic Details
Main Authors: Eva Espinosa-Cano, Maria Rosa Aguilar, Yadileiny Portilla, Domingo F. Barber, Julio San Román
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
nanoparticles
ketoprofen
dexamethasone
inflammation
macrophages
M1 and M2 markers
Online Access:https://www.mdpi.com/1999-4923/12/8/723

Internet

https://www.mdpi.com/1999-4923/12/8/723

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