High Levels of Dual-Class Drug Resistance in HIV-Infected Children Failing First-Line Antiretroviral Therapy in Southern Ethiopia

High Levels of Dual-Class Drug Resistance in HIV-Infected Children Failing First-Line Antiretroviral Therapy in Southern Ethiopia

Clinical monitoring of pediatric HIV treatment remains a major challenge in settings where drug resistance genotyping is not routinely available. As a result, our understanding of drug resistance, and its impact on subsequent therapeutic regimens available in these settings, remains limited. We inve...

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Bibliographic Details
Main Authors: Birkneh Tilahun Tadesse, Natalie N. Kinloch, Bemuluyigza Baraki, Hope R. Lapointe, Kyle D. Cobarrubias, Mark A. Brockman, Chanson J. Brumme, Byron A. Foster, Degu Jerene, Eyasu Makonnen, Eleni Aklillu, Zabrina L. Brumme
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Viruses
Subjects:
HIV
pediatrics
children
Ethiopia
first-line combination antiretroviral therapy (cART)
treatment failure
drug resistance
genotyping
dried blood spots
Online Access:http://www.mdpi.com/1999-4915/10/2/60

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http://www.mdpi.com/1999-4915/10/2/60

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