Arginine Enhances Osteoblastogenesis and Inhibits Adipogenesis through the Regulation of Wnt and NFATc Signaling in Human Mesenchymal Stem Cells

Arginine Enhances Osteoblastogenesis and Inhibits Adipogenesis through the Regulation of Wnt and NFATc Signaling in Human Mesenchymal Stem Cells

Arginine, an α-amino acid, has been reported to exert beneficial effects that ameliorate health problems and prevent excessive fat deposition. In this study, we investigated whether the activation of cell signaling by arginine can induce osteogenic differentiation and modulate excessive adipogenic d...

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Bibliographic Details
Main Authors: Jeong-Eun Huh, Jun-Young Choi, Ye-Ok Shin, Dong-Suk Park, Jung Won Kang, Dongwoo Nam, Do-Young Choi, Jae-Dong Lee
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
arginine
osteoblastogenesis
adipogenesis
NFATc/Wnt signaling pathway
mesenchymal stem cells
Online Access:http://www.mdpi.com/1422-0067/15/7/13010

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http://www.mdpi.com/1422-0067/15/7/13010

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