Regioselectivity and Tautomerism of Novel Five-Membered Ring Nitrogen Heterocycles Formed via Cyclocondensation of Acylthiosemicarbazides

Regioselectivity and Tautomerism of Novel Five-Membered Ring Nitrogen Heterocycles Formed via Cyclocondensation of Acylthiosemicarbazides

A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including fournew compounds, were prepared in order to study substituent effects on cyclizationreactions with oxalyl chloride (producing imidazolidine-4,5-diones 4), dimethylacetylenedicarboxylate (to give thiazolidin-4-ones 7 and 8) an...

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Bibliographic Details
Main Authors: Karel D. Klika, Marián Sabol, Jana PisarÄÂíková, Pavol Kristian, Stanislav Böhm, Ivan Danihel, Ján Imrich, Jana TomaÅ¡ÄÂiková
Format: Article
Language:English
Published: MDPI AG 2008-03-01
Series:Molecules
Subjects:
Acylthiosemicarbazides
imidazolidine-4
5-diones
thiazolidin-4-ones
1
2
4-triazoles
acridines
cytotoxic activity.
Online Access:http://www.mdpi.com/1420-3049/13/3/501/

Internet

http://www.mdpi.com/1420-3049/13/3/501/

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