Co-Expression of Chicken IL-2 and IL-7 Enhances the Immunogenicity and Protective Efficacy of a VP2-Expressing DNA Vaccine against IBDV in Chickens

Chicken infectious bursal disease (IBD) is still incompletely controlled worldwide. Although IBD virus (IBDV) VP2 DNA vaccine was considered a safe vaccine for IBD prevention, the immunogenicity by itself remains poor, resulting in the failure of effectively protecting chickens from infection. We an...

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Bibliographic Details
Main Authors: Shanshan Huo, Jianlou Zhang, Jinghui Fan, Xing Wang, Fengyang Wu, Yuzhu Zuo, Fei Zhong
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/5/476