Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization.

Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization.

Tumor-associated macrophages are known to influence cancer progression by modulation of immune function, angiogenesis, and cell metastasis, however, little is known about the chemokine signaling networks that regulate this process. Utilizing CT26 colon cancer cells and RAW 264.7 macrophages as a mod...

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Bibliographic Details
Main Authors: Chad E Green, Tiffany Liu, Valerie Montel, Gene Hsiao, Robin D Lester, Shankar Subramaniam, Steven L Gonias, Richard L Klemke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2725301?pdf=render

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http://europepmc.org/articles/PMC2725301?pdf=render

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