EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation

EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation

<b>Objective: </b> To investigate the potential of HS-10182, a second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), as a radiosensitizer in non-small cell lung cancer (NSCLC). <b>Methods: </b> Two cell lines of NSCLCs, A549 that possesses w...

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Bibliographic Details
Main Authors: Yang Chen, Youyou Wang, Lujun Zhao, Ping Wang, Jifeng Sun, Rudi Bao, Chenghai Li, Ningbo Liu
Format: Article
Language:English
Published: China Anti-Cancer Association 2018-03-01
Series:Cancer Biology & Medicine
Subjects:
HS-10182
radiosensitization
NSCLC
EGFR-TKI
T790M mutation
radiosensitivity
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1089

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1089

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