Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection

Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection

Existing tumor markers for testicular germ cell tumor (TGCT) cannot detect the presence of pure teratoma. Serum miRNAs have strong performance detecting other subtypes of TGCT. Previous reports suggest high levels of miR-375 expression in teratoma tissue. The purpose of this study was to explore the...

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Bibliographic Details
Main Authors: John T. Lafin, Alexander P. Kenigsberg, Xiaosong Meng, Dreaux Abe, Anna Savelyeva, Nirmish Singla, Solomon L. Woldu, Yair Lotan, Ryan J. Mauck, Cheryl M. Lewis, Vitaly Margulis, Daniel Wong, Liwei Jia, Payal Kapur, Lin Xu, Ryan W. Speir, Gregory T. Chesnut, A. Lindsay Frazier, Douglas W. Strand, Nicholas Coleman, Matthew J. Murray, James F. Amatruda, Aditya Bagrodia
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:European Urology Open Science
Subjects:
Retroperitoneal lymph node dissection
MicroRNA
Teratoma
Serum biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168321000380

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http://www.sciencedirect.com/science/article/pii/S2666168321000380

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