Ischemia-Reperfusion Injury Reduces Kidney Folate Transporter Expression and Plasma Folate Levels

Ischemia-Reperfusion Injury Reduces Kidney Folate Transporter Expression and Plasma Folate Levels

Acute or chronic kidney disease can cause micronutrient deficiency. Patients with end-stage renal disease, kidney transplantation or on dialysis have reduced circulating levels of folate, an essential B vitamin. However, the molecular mechanism is not well understood. Reabsorption of folate in renal...

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Bibliographic Details
Main Authors: Cheng Yang, Charith U. B. Wijerathne, Guo-wei Tu, Connie W. H. Woo, Yaw L. Siow, Susara Madduma Hewage, Kathy K. W. Au-Yeung, Tongyu Zhu, Karmin O
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
acute kidney injury
ischemia
folate
folate transporters
tubular cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.678914/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.678914/full

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