v-SNARE transmembrane domains function as catalysts for vesicle fusion

v-SNARE transmembrane domains function as catalysts for vesicle fusion

Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAREpin to the fusing membranes. Here, we show that c...

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Bibliographic Details
Main Authors: Madhurima Dhara, Antonio Yarzagaray, Mazen Makke, Barbara Schindeldecker, Yvonne Schwarz, Ahmed Shaaban, Satyan Sharma, Rainer A Böckmann, Manfred Lindau, Ralf Mohrmann, Dieter Bruns
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
neurotransmitter release
exocytosis
synaptobrevin
membrane fusion
Online Access:https://elifesciences.org/articles/17571

Internet

https://elifesciences.org/articles/17571

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