Homeostatic Signaling by Cell–Cell Junctions and Its Dysregulation during Cancer Progression

The transition of sessile epithelial cells to a migratory, mesenchymal phenotype is essential for metazoan development and tissue repair, but this program is exploited by tumor cells in order to escape the confines of the primary organ site, evade immunosurveillance, and resist chemo-radiation. In a...

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Bibliographic Details
Main Authors: Yang Yu, Randolph C. Elble
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Journal of Clinical Medicine
Subjects:
EMT
Online Access:http://www.mdpi.com/2077-0383/5/2/26