Homeostatic Signaling by Cell–Cell Junctions and Its Dysregulation during Cancer Progression
The transition of sessile epithelial cells to a migratory, mesenchymal phenotype is essential for metazoan development and tissue repair, but this program is exploited by tumor cells in order to escape the confines of the primary organ site, evade immunosurveillance, and resist chemo-radiation. In a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | http://www.mdpi.com/2077-0383/5/2/26 |