Homeostatic Signaling by Cell–Cell Junctions and Its Dysregulation during Cancer Progression
The transition of sessile epithelial cells to a migratory, mesenchymal phenotype is essential for metazoan development and tissue repair, but this program is exploited by tumor cells in order to escape the confines of the primary organ site, evade immunosurveillance, and resist chemo-radiation. In a...
Main Authors: | Yang Yu, Randolph C. Elble |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | http://www.mdpi.com/2077-0383/5/2/26 |
Similar Items
-
PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression
by: Lindy J. Pence, et al.
Published: (2021-01-01) -
Molecular Characterization of the Extracellular Domain of Human Junctional Adhesion Proteins
by: Christopher Mendoza, et al.
Published: (2021-03-01) -
Tight junctions in Hailey-Hailey and Darier’s diseases
by: Laura Raiko, et al.
Published: (2009-11-01) -
Role of airway epithelial barrier dysfunction in pathogenesis of asthma
by: Yasuhiro Gon, et al.
Published: (2018-01-01) -
Alteration of cell junctions during viral infection
by: Dan Dong, et al.
Published: (2020-03-01)