Modeling Normal and Pathological Ear Cartilage in vitro Using Somatic Stem Cells in Three-Dimensional Culture

Microtia (underdeveloped ear) is a rare congenital dysmorphology affecting the development of the outer ear. Although human microtic cartilage has not been fully characterized, chondrogenic cells derived from this tissue have been proposed as a suitable source for autologous auricular reconstruction...

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Bibliographic Details
Main Authors: Eleonora Zucchelli, Martin Birchall, Neil W. Bulstrode, Patrizia Ferretti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ear
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00666/full