A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus

A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus

Abstract Background Foxp3 is a marker for regulatory T cells (Treg cells), but recent studies have shown the plasticity and heterogeneity of CD4+Foxp3+ T cells. This study aimed to examine the phenotype and function of circulating CD4+Foxp3+ T cells in patients with systemic lupus erythematosus (SLE...

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Bibliographic Details
Main Authors: Hironari Hanaoka, Tetsuya Nishimoto, Yuka Okazaki, Tsutomu Takeuchi, Masataka Kuwana
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Regulatory T cells
Th17
T cell plasticity
Online Access:http://link.springer.com/article/10.1186/s13075-020-02183-2

Internet

http://link.springer.com/article/10.1186/s13075-020-02183-2

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