A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

Abstract Background Avian coronavirus infectious bronchitis virus (IBV) is a respiratory pathogen of chickens that causes severe economic losses in the poultry industry worldwide. Major advances in the study of the molecular biology of IBV have resulted from the development of reverse genetics syste...

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Bibliographic Details
Main Authors: Steven J. van Beurden, Alinda J. Berends, Annika Krämer-Kühl, Dieuwertje Spekreijse, Gilles Chénard, Hans-Christian Philipp, Egbert Mundt, Peter J. M. Rottier, M. Hélène Verheije
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Virology Journal
Subjects:
Avian coronavirus
Infectious bronchitis virus
Mouse hepatitis virus
Targeted RNA recombination
Reverse genetics system
Vaccine development
Online Access:http://link.springer.com/article/10.1186/s12985-017-0775-8

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http://link.springer.com/article/10.1186/s12985-017-0775-8

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