Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages

Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages

The roots and rhizomes of Nardostachys chinensis have neuroprotection and cardiovascular protection effects. However, the specific mechanism of N. chinensis is not yet clear. Nardochinoid C (DC) is a new compound with new skeleton isolated from N. chinensis and this study for the first time explored...

Full description

Bibliographic Details
Main Authors: Jin-Fang Luo, Xiu-Yu Shen, Chon Kit Lio, Yi Dai, Chun-Song Cheng, Jian-Xin Liu, Yun-Da Yao, Yang Yu, Ying Xie, Pei Luo, Xin-Sheng Yao, Zhong-Qiu Liu, Hua Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
Nardostachys chinensis
Nardochinoid C
Nrf2
HO-1
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00911/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00911/full

Similar Items