Gray Matter Densities in Limbic Areas and APOE4 Independently Predict Cognitive Decline in Normal Brain Aging

Gray Matter Densities in Limbic Areas and APOE4 Independently Predict Cognitive Decline in Normal Brain Aging

Cross-sectional magnetic resonance imaging (MRI) studies reported significant associations between gray matter (GM) density changes in various limbic and neocortical areas and worst cognitive performances in elderly controls. Longitudinal studies in this field remain scarce and led to conflicting da...

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Bibliographic Details
Main Authors: François R. Herrmann, Cristelle Rodriguez, Sven Haller, Valentina Garibotto, Marie-Louise Montandon, Panteleimon Giannakopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
longitudinal study
cognition
magnetic resonance imaging
gray matter density
white matter hyperintensity
arterial spin labeling
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00157/full

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00157/full

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