Direct On-Chip Differentiation of Intestinal Tubules from Induced Pluripotent Stem Cells

Direct On-Chip Differentiation of Intestinal Tubules from Induced Pluripotent Stem Cells

Intestinal organoids have emerged as the new paradigm for modelling the healthy and diseased intestine with patient-relevant properties. In this study, we show directed differentiation of induced pluripotent stem cells towards intestinal-like phenotype within a microfluidic device. iPSCs are culture...

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Bibliographic Details
Main Authors: Elena Naumovska, Germaine Aalderink, Christian Wong Valencia, Kinga Kosim, Arnaud Nicolas, Stephen Brown, Paul Vulto, Kai S. Erdmann, Dorota Kurek
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
iPSC
intestinal organoids
directed differentiation
gut-on-a-chip
organ-on-a-chip
microfluidics
Online Access:https://www.mdpi.com/1422-0067/21/14/4964

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https://www.mdpi.com/1422-0067/21/14/4964

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