Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers.

Cancer is characterized by uncontrolled cell growth, and the cause of different cancers is generally attributed to checkpoint dysregulation of cell proliferation and apoptosis. Recent studies have shown that non-optimal codons were preferentially adopted by genes to generate cell cycle-dependent osc...

Full description

Bibliographic Details
Main Authors: Xudong Wu, Guohui Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4981346?pdf=render