Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials

Clustering of continuous and binary outcomes at the general practice level in individually randomised studies in primary care - a review of 10 years of primary care trials

Abstract Background In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are natura...

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Bibliographic Details
Main Authors: Beth Stuart, Taeko Becque, Michael Moore, Paul Little
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Research Methodology
Subjects:
Clustering
Intra-cluster correlation
Individually randomised trial
GP practice
Primary care
Online Access:http://link.springer.com/article/10.1186/s12874-020-00971-7

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http://link.springer.com/article/10.1186/s12874-020-00971-7

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