Prima-1 induces apoptosis in bladder cancer cell lines by activating p53

Prima-1 induces apoptosis in bladder cancer cell lines by activating p53

OBJECTIVES: Bladder cancer represents 3% of all carcinomas in the Brazilian population and ranks second in incidence among urological tumors, after prostate cancer. The loss of p53 function is the main genetic alteration related to the development of high-grade muscle-invasive disease. Prima-1 is a...

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Bibliographic Details
Main Authors: Camila B. Piantino, Sabrina T. Reis, Nayara I. Viana, Iran A. Silva, Denis R. Morais, Alberto A. Antunes, Nelson Dip, Miguel Srougi, Katia R. Leite
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2013-01-01
Series:Clinics
Subjects:
Bladder cancer
p53
Apoptosis
Prima-1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000300004

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000300004

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